tert-butyl azetidin-3-yl(methyl)carbamate

tert-butyl azetidin-3-yl(methyl)carbamate

tert-butyl 3-(2-methoxy-2-oxoethyl)azetidine-1-carboxylate

tert-butyl 3-(2-methoxy-2-oxoethyl)azetidine-1-carboxylate

3-hydroxy-1-methylazetidine

$350.00
CAS No.: 111043-48-2
Catalog No.: 111093
Purity: 95%
MF: C4H9NO
MW: 87.122
Storage: 2-8 degree Celsius
SMILES: CN1CC(O)C1
Availability:
In stock
SKU
111093
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3-hydroxy-1-methylazetidine; CAS No.: 111043-48-2; Specializing in hydroxylated azetidines, ChemShuttle offers 3-hydroxy-1-methylazetidine for prodrug development. This secondary alcohol combines ring strain for reactivity with methyl substitution for metabolic stability. The compound's molecular weight 101.15 and calculated PSA 33 ?2 balance solubility and membrane permeability. Our chemical synthesis companies developed a novel reduction method to achieve high diastereoselectivity in ring formation. The hydroxyl group enables esterification or oxidation to ketones, while the methyl group blocks undesirable metabolic pathways. We provide guidance on handling moisture-sensitive azetidines and offer custom salt formation services. Technical documents include pKa determination data and excipient compatibility studies.

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