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1-(diphenylmethyl)-2,2-dimethylazetidin-3-ol; CAS No.: 159556-73-7; 1-(diphenylmethyl)-2,2-dimethylazetidin-3-ol. PROPERTIES: 1-(diphenylmethyl)-2,2-dimethylazetidin-3-ol appears as a white to off-white crystalline powder with a slight odor. Its molecular formula is C18H20NO, corresponding to a molecular weight of approximately 272.36 g/mol. The compound exhibits a melting point in the range of 140-145 C and demonstrates moderate solubility in common organic solvents such as methanol, ethyl acetate, and dichloromethane while being sparingly soluble in water. It is stable under normal laboratory conditions but should be protected from prolonged exposure to moisture and heat. Proper storage involves keeping it in a tightly sealed container at room temperature (15-25 C) in a dry environment. Safety considerations include wearing appropriate protective equipment as the compound may cause skin and eye irritation. Inhalation of dust should be avoided, and in case of accidental exposure, thorough washing with water and medical consultation is advised. APPLICATIONS: 1-(diphenylmethyl)-2,2-dimethylazetidin-3-ol serves as a valuable intermediate in the synthesis of pharmaceuticals, particularly in the preparation of certain antidepressants and antipsychotics. Its azetidine and diphenylmethyl groups provide structural features important for receptor binding and bioactivity. In biochemical research, it functions as a building block for creating enzyme inhibitors and prodrugs. Additionally, it finds application in the development of fluorescent probes for bioimaging, where its hydroxyl group allows for selective labeling of biological targets such as proteins and lipids. The compound is also employed in the synthesis of agrochemicals, though specific applications in this area are limited to non-agricultural research settings.