2,4-dihydroxypyrimidine-5-carboxylic acid
$400.00
CAS No.: 23945-44-0
Catalog No.: 196408
Purity: 95%
MF: C5H4N2O4
MW: 156.097
Storage: 2-8 degree Celsius
SMILES: OC1=NC=C(C(=N1)O)C(=O)O
Catalog No.: 196408
Purity: 95%
MF: C5H4N2O4
MW: 156.097
Storage: 2-8 degree Celsius
SMILES: OC1=NC=C(C(=N1)O)C(=O)O
2,4-dihydroxypyrimidine-5-carboxylic acid; CAS No.: 23945-44-0; 2,4-dihydroxypyrimidine-5-carboxylic acid. PROPERTIES: This compound features a 2,4-dihydroxypyrimidine-5-carboxylic acid structure, combining two hydroxyl groups and a carboxylic acid on the pyrimidine framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 182.1 g/mol (C4H4N2O4). The melting point ranges between 190-195 C, and it exhibits moderate solubility in common organic solvents like ethanol, methanol, and DMSO while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 2,4-Dihydroxypyrimidine-5-carboxylic acid serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 2,4-dihydroxypyrimidine-5-carboxylic acid structure allows for participation in various reactions, including esterification, amide bond formation, and nucleophilic substitution at the pyrimidine ring. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The hydroxyl groups can be modified through etherification or esterification. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel dihydroxypyrimidine derivatives based on the 2,4-dihydroxypyrimidine-5-carboxylic acid scaffold.
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