2-(4-bromo-1H-pyrazol-1-yl)-N,N-dimethylethan-1-amine
$550.00
CAS No.: 847818-54-6
Catalog No.: 196948
Purity: 95%
MF: C7H12BrN3
MW: 218.098
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NN(C1)CCN(C)C
Catalog No.: 196948
Purity: 95%
MF: C7H12BrN3
MW: 218.098
Storage: 2-8 degree Celsius
SMILES: BrC=1C=NN(C1)CCN(C)C
2-(4-bromo-1H-pyrazol-1-yl)-N,N-dimethylethan-1-amine; CAS No.: 847818-54-6; 2-(4-bromo-1H-pyrazol-1-yl)-N,N-dimethylethan-1-amine. PROPERTIES: This bromo-substituted pyrazole amine features molecular formula C?H??BrN? with molecular weight 215.09 g/mol. It typically exists as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 100-105 C. Exhibits IR absorption for amine (~3300-3000 cm??) and C-Br groups (~600-500 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a bromo-substituted pyrazole amine, 2-(4-bromo-1H-pyrazol-1-yl)-N,N-dimethylethan-1-amine is predominantly utilized in the synthesis of kinase inhibitors. It serves as a key intermediate in constructing the core scaffold of these compounds, where the pyrazole ring provides valuable binding affinity for the kinase active site as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its amine functionality enables conjugation to fluorophores via reductive amination (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the bromo substituent contributes to improved flame retardancy and mechanical properties (Polymer International).
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