3-hydroxy-1-methyl-5-(trifluoromethyl)pyrazole
$250.00
CAS No.: 119022-51-4
Catalog No.: 196955
Purity: 95%
MF: C5H5F3N2O
MW: 166.102
Storage: 2-8 degree Celsius
SMILES: OC1=NN(C(=C1)C(F)(F)F)C
Catalog No.: 196955
Purity: 95%
MF: C5H5F3N2O
MW: 166.102
Storage: 2-8 degree Celsius
SMILES: OC1=NN(C(=C1)C(F)(F)F)C
3-hydroxy-1-methyl-5-(trifluoromethyl)pyrazole; CAS No.: 119022-51-4; 3-hydroxy-1-methyl-5-(trifluoromethyl)pyrazole. PROPERTIES: This hydroxy-substituted pyrazole features molecular formula C?H?F?N?O with molecular weight 167.11 g/mol. It generally appears as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 120-125 C. Exhibits IR absorption for hydroxyl groups (~3300 cm??) and C-F stretches (~1300-1100 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a hydroxy-substituted pyrazole, 3-hydroxy-1-methyl-5-(trifluoromethyl)pyrazole is predominantly utilized in the synthesis of agrochemicals. It serves as a key intermediate in constructing pyrazole-based herbicides, where the hydroxyl and trifluoromethyl groups provide valuable binding affinity for plant enzymes as demonstrated in pesticide chemistry research (Pest Management Science). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its pyrazole framework enables conjugation to fluorophores with enhanced photostability (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the trifluoromethyl group contributes to improved flame retardancy and mechanical properties (Polymer International).
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