2-fluoro-5-nitrobenzoyl chloride
$200.00
CAS No.: 709-46-6
Catalog No.: 193932
Purity: 95%
MF: C7H3ClFNO3
MW: 203.556
Storage: 2-8 degree Celsius
SMILES: FC1=C(C(=O)Cl)C=C(C=C1)[N+](=O)[O-]
Catalog No.: 193932
Purity: 95%
MF: C7H3ClFNO3
MW: 203.556
Storage: 2-8 degree Celsius
SMILES: FC1=C(C(=O)Cl)C=C(C=C1)[N+](=O)[O-]
2-fluoro-5-nitrobenzoyl chloride; CAS No.: 709-46-6;2-fluoro-5-nitrobenzoyl chloride. PROPERTIES: 2-fluoro-5-nitrobenzoyl chloride is a fluorinated and nitrated aromatic acid chloride with molecular formula C7H4ClFNO3. It typically exists as a colorless to pale yellow liquid with a boiling point around 130-135 C. The compound has limited water solubility but dissolves well in organic solvents like dichloromethane or carbon tetrachloride. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong bases, releasing toxic nitrogen oxides and chlorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile building block for creating complex aromatic systems. The fluoro substituent provides electron-withdrawing effects, while the nitro and acid chloride groups offer multiple sites for further functionalization (Tetrahedron Letters). In pharmaceutical development, 2-fluoro-5-nitrobenzoyl chloride contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Journal of Materials Chemistry C).
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