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CAS NO.: 1871-76-7; diphenylacetyl chloride. PROPERTIES: This acyl chloride features a diphenylacetyl group, creating a molecule with potential applications in organic synthesis and pharmaceutical research. The diphenylacetyl chloride typically appears as a colorless to pale yellow liquid with low aqueous solubility but good solubility in common organic solvents. Its molecular structure includes an electrophilic acyl chloride functionality that renders the molecule highly reactive toward nucleophilic acylation reactions. For optimal stability and to prevent premature reactions, this compound should be stored at 2-8 degree Celsius in an amber glass bottle under an inert atmosphere. When handling, appropriate safety measures including nitrile gloves, safety goggles, and proper ventilation are essential. This compound is sensitive to moisture and may undergo hydrolysis to form the corresponding carboxylic acid. In case of skin contact, wash immediately with soap and water; if eye contact occurs, rinse thoroughly and seek medical evaluation. APPLICATIONS: The diphenylacetyl chloride serves as a versatile building block in organic synthesis, particularly for creating amide and ester bonds in complex molecules. The acyl chloride group provides a handle for efficient coupling reactions with amines and alcohols. In medicinal chemistry, this compound functions as an intermediate for developing pharmaceuticals targeting enzyme inhibitors and receptor modulators. The diphenylacetyl group contributes to target binding affinity and selectivity. Additionally, the molecule finds utility in materials science as a monomer for creating polymers with specific electronic and optical properties. Researchers utilizing this compound can benefit from its high reactivity and functional group compatibility, enabling the development of diverse molecular architectures for applications ranging from drug discovery to advanced materials.