3-(4-aminophenyl)-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-amine
$300.00
CAS No.: 54628-90-9
Catalog No.: 197211
Purity: 95%
MF: C18H22N2
MW: 266.388
Storage: 2-8 degree Celsius
SMILES: NC1=CC=C(C=C1)C1(CC(C2=CC=C(C=C12)N)(C)C)C
Catalog No.: 197211
Purity: 95%
MF: C18H22N2
MW: 266.388
Storage: 2-8 degree Celsius
SMILES: NC1=CC=C(C=C1)C1(CC(C2=CC=C(C=C12)N)(C)C)C
3-(4-aminophenyl)-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-amine; CAS No.: 54628-90-9; 3-(4-aminophenyl)-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-amine. PROPERTIES: This amino-substituted indane amine features molecular formula C??H??N? with molecular weight 238.33 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 120-125 C. Exhibits IR absorption for amine (~3300-3000 cm??) and aromatic C-H stretches. Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As an amino-substituted indane amine, 3-(4-aminophenyl)-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-amine is predominantly utilized in the synthesis of kinase inhibitors. It serves as a key intermediate in constructing the core scaffold of these compounds, where the indane and amine groups provide valuable binding affinity for the kinase active site as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its amine functionality enables conjugation to fluorophores via reductive amination (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the indane group contributes to improved flame retardancy and mechanical properties (Polymer International).
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