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Fmoc-D-Dap(mtt)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((diphenyl(p-tolyl)methyl)amino)propanoicacid; CAS No.: 1263046-35-0; Fmoc-D-Dap(mtt)-OH. PROPERTIES: Fmoc-D-Dap(mtt)-OH is a protected amino acid derivative used in peptide synthesis. This compound has a molecular weight of approximately 500-600 g/mol and appears as a white to slightly yellowish solid. It is sparingly soluble in water but dissolves in organic solvents like DMF and dichloromethane. Fmoc-D-Dap(mtt)-OH should be stored at room temperature in a dry, dark environment. It is sensitive to moisture and light. Safety precautions include avoiding inhalation and skin contact as it may cause irritation. APPLICATIONS: Fmoc-D-Dap(mtt)-OH serves as a building block in the synthesis of peptides containing D-2,4-diaminobutyric acid residues with mtt protection on the side chain amino group. In medicinal chemistry, it facilitates the creation of peptidomimetics with enhanced conformational constraints. In research applications, Fmoc-D-Dap(mtt)-OH is used to prepare peptides for studying protein-protein interactions and enzyme inhibition mechanisms. These applications are referenced in peptide chemistry literature and synthetic organic chemistry publications.