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tert-butyl methyl(3-(methylamino)propyl)carbamate; CAS No.: 123183-72-2; tert-butyl methyl(3-(methylamino)propyl)carbamate. PROPERTIES: This methylamino-substituted carbamate features molecular formula C??H??N?O? with molecular weight 196.28 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like ethyl acetate and dichloromethane. Melting point approximately 90-95 C. Exhibits IR absorption for carbamate (~1700 cm??) and amine groups (~3300-3000 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a methylamino-substituted carbamate, tert-butyl methyl(3-(methylamino)propyl)carbamate is predominantly utilized in the synthesis of peptide-based therapeutics. It serves as a key building block for constructing bioactive peptides with enhanced conformational stability, particularly in the development of enzyme inhibitors targeting proteases (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its carbamate functionality enables conjugation to biomolecules via amide bond formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the methylamino group contributes to improved flame retardancy and mechanical properties (Polymer International).