(R)-tert-butyl (3-amino-2-hydroxypropyl)carbamate
$300.00
CAS No.: 1042665-73-5
Catalog No.: 193175
Purity: 95%
MF: C8H18N2O3
MW: 190.243
Storage: 2-8 degree Celsius
SMILES: NC[C@H](CNC(OC(C)(C)C)=O)O
Catalog No.: 193175
Purity: 95%
MF: C8H18N2O3
MW: 190.243
Storage: 2-8 degree Celsius
SMILES: NC[C@H](CNC(OC(C)(C)C)=O)O
(R)-tert-butyl (3-amino-2-hydroxypropyl)carbamate; CAS No.: 1042665-73-5; (R)-tert-butyl (3-amino-2-hydroxypropyl)carbamate. PROPERTIES: This compound is a (R)-tert-butyl (3-amino-2-hydroxypropyl)carbamate appearing as white crystalline solid. Its molecular weight is approximately 221.28 g/mol. It has melting point around 105-110 C. The compound is moderately soluble in polar aprotic solvents like dimethylformamide. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 20 C and protect from moisture. Handle with care using appropriate engineering controls to prevent dust inhalation. APPLICATIONS: (R)-tert-butyl (3-amino-2-hydroxypropyl)carbamate is utilized in asymmetric synthesis as chiral amine building block as detailed in Journal of Organic Chemistry. It's employed in preparation of certain ACE inhibitor prodrugs mentioned in Journal of Medicinal Chemistry. Additionally, this compound serves as intermediate for synthesizing beta-amino alcohol containing pharmaceuticals reported in Organic Process Research & Development. The chiral center provides valuable stereochemical control in drug discovery projects.
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