Hydroxy-PEG6-t-butyl ester
$500.00
CAS No.: 361189-64-2
Catalog No.: 193643
Purity: 95%
MF: C19H38O9
MW: 410.504
Storage: 2-8 degree Celsius
SMILES: OCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C
Catalog No.: 193643
Purity: 95%
MF: C19H38O9
MW: 410.504
Storage: 2-8 degree Celsius
SMILES: OCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C
Hydroxy-PEG6-t-butyl ester; tert-butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate; CAS No.: 361189-64-2; Hydroxy-PEG6-t-butyl ester. PROPERTIES: Hydroxy-PEG6-t-butyl ester is a viscous, colorless liquid with the molecular formula C14H26O7. It exhibits good solubility in water and polar organic solvents like methanol and ethyl acetate. The compound is stable at room temperature but should be stored in a tightly closed container to prevent moisture absorption. Safety precautions include avoiding prolonged skin contact due to its potential irritant properties and using proper ventilation during handling. With a molecular weight of approximately 318.35 g/mol, it has a low vapor pressure and high viscosity, making it suitable for various conjugation reactions. The compound demonstrates hydrophilic properties due to the polyethylene glycol (PEG) chain, which significantly affects its solubility and biocompatibility. Its molecular structure includes a terminal hydroxyl group and a tert-butyl ester protecting group. APPLICATIONS: Hydroxy-PEG6-t-butyl ester serves as a PEGylation reagent in pharmaceutical research, used to modify proteins, peptides, and small molecules to improve their pharmacokinetic profiles. In drug development, it is employed to increase the solubility and stability of therapeutic agents while reducing immunogenicity. The compound is used in bioconjugation chemistry to create PEGylated drug delivery systems and in the synthesis of polymeric nanoparticles for targeted therapy. Additionally, it functions as a building block in materials science for creating hydrogels and surface coatings with controlled release properties. As described in "PEGylation: The Development and Application of Polyethylene Glycol in Drug Delivery," this PEG derivative provides versatile functionality for enhancing therapeutic performance across multiple drug classes.
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