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3-amino-3-methyl-1-pentyne hydrochloride; CAS No.: 108575-32-2; 3-amino-3-methyl-1-pentyne hydrochloride. PROPERTIES: This compound is a 3-amino-3-methyl-1-pentyne hydrochloride appearing as white crystalline powder. Its molecular weight is approximately 157.21 g/mol (free base). It has melting point around 130-135 C (with decomposition). The compound is moderately soluble in water and polar organic solvents. It's moisture sensitive and may degrade upon exposure to humidity. Store in tightly sealed containers under dry conditions. Keep below 30 C and protect from moisture. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: 3-amino-3-methyl-1-pentyne hydrochloride is utilized in organic synthesis as alkyne building block containing amine functionality as detailed in Organic Letters. It's employed in preparation of certain HIV protease inhibitors mentioned in Journal of Medicinal Chemistry. Additionally, this compound serves as intermediate for synthesizing ynamin-containing pharmaceuticals reported in Bioorganic & Medicinal Chemistry Letters. The terminal alkyne group provides opportunity for click chemistry reactions in drug discovery projects.