3,3,3-trifluoro-2,2-dimethylpropan-1-ol
$360.00
CAS No.: 1895296-01-1
Catalog No.: 197222
Purity: 95%
MF: C5H9F3O
MW: 142.12
Storage: 2-8 degree Celsius
SMILES: FC(C(CO)(C)C)(F)F
Catalog No.: 197222
Purity: 95%
MF: C5H9F3O
MW: 142.12
Storage: 2-8 degree Celsius
SMILES: FC(C(CO)(C)C)(F)F
3,3,3-trifluoro-2,2-dimethylpropan-1-ol; CAS No.: 1895296-01-1; 3,3,3-trifluoro-2,2-dimethylpropan-1-ol. PROPERTIES: This trifluoro-dimethyl-substituted propanol features molecular formula C?H?F?O? with molecular weight 158.13 g/mol. It generally appears as a colorless liquid. Soluble in polar aprotic solvents like DMF and DMSO. Boiling point approximately 130-135 C. Exhibits IR absorption for hydroxyl groups (~3300 cm??) and C-F groups (~1300-1100 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a trifluoro-dimethyl-substituted propanol, 3,3,3-trifluoro-2,2-dimethylpropan-1-ol is predominantly utilized in the synthesis of liquid crystal materials. It serves as a key intermediate in constructing mesogenic units for liquid crystal displays, where the trifluoromethyl group provides valuable polarity for alignment and response properties as demonstrated in materials science research (Liquid Crystals). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its hydroxyl group forms covalent bonds with target biomolecules via oxime formation (Bioconjugate Chemistry). In medicinal chemistry, it functions as a building block for constructing kinase inhibitors, where the trifluoromethyl group provides valuable binding affinity for the kinase hinge region (Journal of Medicinal Chemistry).
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