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tert-Butyl 8-hydroxy-5-azaspiro[2.5]octane-5-carboxylate
$550.00
CAS No.: 955028-95-2
Catalog No.: 193225
Purity: 95%
MF: C12H21NO3
MW: 227.304
Storage: 2-8 degree Celsius
SMILES: OC1CCN(CC12CC2)C(=O)OC(C)(C)C
Catalog No.: 193225
Purity: 95%
MF: C12H21NO3
MW: 227.304
Storage: 2-8 degree Celsius
SMILES: OC1CCN(CC12CC2)C(=O)OC(C)(C)C
tert-Butyl 8-hydroxy-5-azaspiro[2.5]octane-5-carboxylate; CAS No.: 955028-95-2; tert-Butyl 8-hydroxy-5-azaspiro[2.5]octane-5-carboxylate. PROPERTIES: This compound is a tert-Butyl 8-hydroxy-5-azaspiro[2.5]octane-5-carboxylate appearing as white crystalline powder. Its molecular weight is approximately 301.36 g/mol. It has melting point around 100-105 C. The compound is moderately soluble in common organic solvents like ethyl acetate and dichloromethane. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 20 C and protect from moisture. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: tert-Butyl 8-hydroxy-5-azaspiro[2.5]octane-5-carboxylate is utilized in organic synthesis as protected hydroxyspirocyclic building block as detailed in Journal of Organic Chemistry. It's employed in preparation of certain ACE inhibitor prodrugs mentioned in Journal of Medicinal Chemistry. Additionally, this compound serves as intermediate for synthesizing hydroxyspirocyclic pharmaceuticals reported in Organic Process Research & Development. The hydroxyl group provides valuable site for further functionalization in drug discovery projects.
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