tert-Butyl ((1R,2R)-2-(hydroxymethyl)cyclopropyl)carbamate
$350.00
CAS No.: 177472-54-7
Catalog No.: 193271
Purity: 95%
MF: C9H17NO3
MW: 187.239
Storage: 2-8 degree Celsius
SMILES: OC[C@H]1[C@@H](C1)NC(OC(C)(C)C)=O
Catalog No.: 193271
Purity: 95%
MF: C9H17NO3
MW: 187.239
Storage: 2-8 degree Celsius
SMILES: OC[C@H]1[C@@H](C1)NC(OC(C)(C)C)=O
tert-Butyl ((1R,2R)-2-(hydroxymethyl)cyclopropyl)carbamate; CAS No.: 177472-54-7; tert-Butyl ((1R,2R)-2-(hydroxymethyl)cyclopropyl)carbamate. PROPERTIES: This compound is a tert-Butyl ((1R,2R)-2-(hydroxymethyl)cyclopropyl)carbamate appearing as white crystalline powder. Its molecular weight is approximately 234.30 g/mol. It has melting point around 70-75 C. The compound is moderately soluble in common organic solvents like ethyl acetate and dichloromethane. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 20 C and protect from moisture. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: tert-Butyl ((1R,2R)-2-(hydroxymethyl)cyclopropyl)carbamate is utilized in organic synthesis as protected aminohydroxymethylcyclopropyl building block as detailed in Journal of Organic Chemistry. It's employed in preparation of certain beta-blockers with specific stereochemistry mentioned in Journal of Medicinal Chemistry. Additionally, this compound serves as intermediate for synthesizing cyclopropyl-containing pharmaceuticals reported in Organic Process Research & Development. The tert-butoxycarbonyl group provides valuable temporary protection for amine functionality during multi-step synthesis.
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