N-hydroxycyclopropanecarboximidamide
$300.00
CAS No.: 51285-13-3
Catalog No.: WLZ1878
Purity: 95%
MF: C4H8N2O
MW: 100.121
Storage: 2-8 degree Celsius
SMILES: ONC(=N)C1CC1
Catalog No.: WLZ1878
Purity: 95%
MF: C4H8N2O
MW: 100.121
Storage: 2-8 degree Celsius
SMILES: ONC(=N)C1CC1
CAS NO.: 51285-13-3; N-hydroxycyclopropanecarboximidamide. PROPERTIES: This carboximidamide features a hydroxy group and a cyclopropane ring connected to an amidine group, creating a molecule with potential applications in organic synthesis and pharmaceutical research. The N-hydroxycyclopropanecarboximidamide typically appears as a white crystalline powder with moderate aqueous solubility. Its molecular structure includes a cyclopropane ring that influences the electronic properties and reactivity of the molecule. For optimal stability, this compound should be stored at 2-8 degree Celsius in a tightly sealed container away from moisture and direct light. When handling, chemists should wear appropriate personal protective equipment including nitrile gloves and safety goggles. This compound is hygroscopic and may form salts upon exposure to atmospheric moisture. In case of accidental ingestion, rinse mouth thoroughly and seek medical attention. APPLICATIONS: The N-hydroxycyclopropanecarboximidamide serves as a valuable intermediate in the synthesis of pharmaceuticals, particularly those targeting enzyme inhibitors and receptor modulators. The amidine and hydroxy groups provide bioisosteric replacements that can enhance metabolic stability and target binding affinity. In medicinal chemistry, this compound functions as a building block for developing antiviral and anticancer agents where the cyclopropane ring contributes to target engagement. Additionally, the molecule finds utility in chemical biology studies where its unique scaffold can be used to probe enzyme inhibition mechanisms and cellular signaling pathways. Researchers utilizing this compound benefit from its defined electronic properties and functional group arrangement, advancing investigations into novel therapeutic approaches for various disease conditions.
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