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2-amino-2-cyclobutylacetic acid; CAS No.: 28024-69-3; 2-Amino-2-cyclobutylacetic acid offers a conformationally restricted amino acid for peptide backbone modification. The cyclobutyl group induces -sheet breaking in peptide structures. As a leading chemicals distributor, we provide non-proteogenic amino acids with various ring sizes. Our synthesis employs Strecker amino acid synthesis with enantioselective crystallization. The compound's strain energy enhances binding affinity in peptide-protein interaction studies.