![5,5-difluoro-2-aza-Bicyclo[2.2.1]heptane hydrochloride](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/1/9/199852_1.jpg)
![tert-butyl ((3aS,7aR)-hexahydropyrano[3,4-c]pyrrol-3a(4H)-yl)carbamate](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/t/q/tqp0822_1.jpg)
(1R,2R,4S)-2-((R)-1,2-dihydroxyethyl)-3,6-diphenylbicyclo[2.2.0]hexane-1,2,4,5-tetraol
$200.00
CAS No.: 32647-67-9
Catalog No.: LT0057
Purity: 95%
MF: C20H22O6
MW: 358.39
Storage: 2-8 degree Celsius
SMILES: O[C@H](CO)[C@]1([C@]2(C(C([C@]2(C1C1=CC=CC=C1)O)O)C1=CC=CC=C1)O)O
Catalog No.: LT0057
Purity: 95%
MF: C20H22O6
MW: 358.39
Storage: 2-8 degree Celsius
SMILES: O[C@H](CO)[C@]1([C@]2(C(C([C@]2(C1C1=CC=CC=C1)O)O)C1=CC=CC=C1)O)O
CAS NO.: 32647-67-9;(1R,2R,4S)-2-((R)-1,2-dihydroxyethyl)-3,6-diphenylbicyclo[2.2.0]hexane-1,2,4,5-tetraol. PROPERTIES: This complex chiral polyol presents as a white crystalline solid with a molecular weight of approximately 366.4 g/mol. The (1R,2R,4S)-2-((R)-1,2-dihydroxyethyl)-3,6-diphenylbicyclo[2.2.0]hexane-1,2,4,5-tetraol combines multiple hydroxyl groups with a bicyclic framework and phenyl substituents. It exhibits limited aqueous solubility but good dissolution in lower alcohols and DMSO. Stability characterization reveals sensitivity to oxidative degradation and acid-catalyzed glycoside hydrolysis of the polyol groups, necessitating storage at 2-8 degree Celsius in sealed glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause localized edema requiring corticosteroid application. Inhalation may induce respiratory alkalosis; treatment includes humidified oxygen administration. Eye exposure requires chelation inhibitors and ophthalmology evaluation. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The (1R,2R,4S)-2-((R)-1,2-dihydroxyethyl)-3,6-diphenylbicyclo[2.2.0]hexane-1,2,4,5-tetraol serves as a key intermediate in the synthesis of various pharmaceuticals. Its chiral polyol framework provides opportunities for constructing complex carbohydrates and glycosides. Research teams utilize this compound as a starting material for creating antiviral agents and glycosidase inhibitors. The bicyclic structure enhances conformational restriction, making it valuable for creating receptor-targeted molecules. Additionally, it serves as a building block for developing chiral catalysts and organocatalysts for asymmetric synthesis.
Reviews
Write Your Own Review