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2-azabicyclo[2.2.2]octan-3-one; CAS No.: 3306-69-2; 2-Azabicyclo[2.2.2]octan-3-one showcases our strained bicyclic amine derivatives for allosteric modulator development. The quinuclidine core provides rigid tertiary amine geometry for nicotinic receptor studies. As a worldwide chemical supplier, we offer both ketone and alcohol derivatives of this scaffold. Our synthetic route utilizes catalytic hydrogenation under high pressure to construct the bridged ring system. The ketone functionality allows reductive amination for introducing diverse substituents.