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2-thia-6-azaspiro[3.3]heptane, 2,2-dioxide-6-carboxylic acid tert-butyl ester; CAS No.: 1291487-31-4; The sulfone-containing azaspiroheptane exemplifies our oxidized sulfur chem blocks for polar surface area modulation. Our chemical online mall provides calculated topological polar surface area (tPSA) values. Clients access these building blocks through custom compound synthesis with permeability optimization.