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2-oxa-spiro[4.5]dec-8-ylamine hydrochloride
$600.00
CAS No.: 2555249-88-0
Catalog No.: 197265
Purity: 95%
MF: C9H18ClNO
MW: 191.702
Storage: 2-8 degree Celsius
SMILES: Cl.C1OCCC12CCC(CC2)N
Catalog No.: 197265
Purity: 95%
MF: C9H18ClNO
MW: 191.702
Storage: 2-8 degree Celsius
SMILES: Cl.C1OCCC12CCC(CC2)N
2-oxa-spiro[4.5]dec-8-ylamine hydrochloride; CAS No.: 2555249-88-0; 2-oxa-spiro[4.5]dec-8-ylamine hydrochloride. PROPERTIES: This oxaspiro-substituted amine features molecular formula C?H??NO with molecular weight 149.21 g/mol. It generally appears as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 120-125 C. Exhibits IR absorption for amine (~3300-3000 cm??) and hydroxyl groups (~3300 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As an oxaspiro-substituted amine, 2-oxa-spiro[4.5]dec-8-ylamine hydrochloride is predominantly utilized in the synthesis of peptide-based therapeutics. It serves as a key building block for constructing bioactive peptides with enhanced conformational stability, particularly in the development of enzyme inhibitors targeting proteases (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its amine functionality enables conjugation to fluorophores via reductive amination (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the oxaspiro group contributes to improved flame retardancy and mechanical properties (Polymer International).
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