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(6-bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol
$360.00
CAS No.: 280752-78-5
Catalog No.: HKP0273
Purity: 95%
MF: C9H9BrO3
MW: 245.072
Storage: 2-8 degree Celsius
SMILES: BrC1=CC2=C(OC(CO2)CO)C=C1
Catalog No.: HKP0273
Purity: 95%
MF: C9H9BrO3
MW: 245.072
Storage: 2-8 degree Celsius
SMILES: BrC1=CC2=C(OC(CO2)CO)C=C1
CAS NO.: 280752-78-5;(6-bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol. PROPERTIES: This brominated methanol derivative presents as a white crystalline solid with a molecular weight of approximately 259.0 g/mol. The (6-bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol combines a bromine substituent with a methanol group on a dioxin ring system. It exhibits limited aqueous solubility but good dissolution in polar aprotic solvents like DMSO and DMF. Stability characterization reveals sensitivity to oxidative degradation and light exposure, necessitating storage at 2-8 degree Celsius in amber glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause mild irritation requiring thorough washing. Inhalation may induce respiratory tract irritation; treatment includes fresh air and medical evaluation. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The (6-bromo-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol serves as a key intermediate in the synthesis of various pharmaceuticals. Its bromine substituent provides a valuable handle for cross-coupling reactions. Research teams utilize this compound as a starting material for creating serotonin receptor modulators and antipsychotic agents. The methanol group undergoes oxidation to form carboxylic acids or alkylation for further functionalization. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity.
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