5-bromo-4-methylthiazol-2-amine hydrochloride
$200.00
CAS No.: 133692-16-7
Catalog No.: 196066
Purity: 95%
MF: C4H6BrClN2S
MW: 229.53
Storage: 2-8 degree Celsius
SMILES: Cl.BrC1=C(N=C(S1)N)C
Catalog No.: 196066
Purity: 95%
MF: C4H6BrClN2S
MW: 229.53
Storage: 2-8 degree Celsius
SMILES: Cl.BrC1=C(N=C(S1)N)C
5-bromo-4-methylthiazol-2-amine hydrochloride; CAS No.: 133692-16-7; 5-bromo-4-methylthiazol-2-amine hydrochloride. PROPERTIES: 5-bromo-4-methylthiazol-2-amine hydrochloride is a crystalline salt with a molecular weight of approximately 240.5 g/mol. It has a melting point around 190-195 C (decomposition). The compound is highly water-soluble due to the hydrochloride salt form but has limited solubility in organic solvents. It is hygroscopic and should be stored in airtight containers at controlled humidity. The presence of the bromine atom imparts significant mass to the molecule, affecting its physical properties. The amine functionality is fully protonated in the hydrochloride form, which influences its reactivity. Safety: This compound may cause respiratory tract irritation. In case of ingestion, rinse mouth immediately and seek medical advice. Avoid contact with foodstuffs and use only in well-ventilated areas. In case of fire, use appropriate extinguishing media suitable for chemical fires. APPLICATIONS: In pharmaceutical development, 5-bromo-4-methylthiazol-2-amine hydrochloride serves as a lead compound for antibacterial agents. The bromine substituent enhances penetration through bacterial cell walls, while the thiazole ring provides structural rigidity. In medicinal chemistry, it is used as a building block for kinase inhibitors. The amine group participates in hydrogen bonding with enzyme active sites. In agrochemical research, derivatives of this compound are explored for herbicidal applications. The bromine atom contributes to selectivity between plant and mammalian systems. These applications are supported by research articles in pharmaceutical chemistry and agrochemical journals.
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