3-cyclobutyl-1H-pyrazol-5-amine
$250.00
CAS No.: 326827-21-8
Catalog No.: 170404
Purity: 95%
MF: C7H11N3
MW: 137.186
Storage: 2-8 degree Celsius
SMILES: NC1=CC(=NN1)C1CCC1
Catalog No.: 170404
Purity: 95%
MF: C7H11N3
MW: 137.186
Storage: 2-8 degree Celsius
SMILES: NC1=CC(=NN1)C1CCC1
3-cyclobutyl-1H-pyrazol-5-amine; CAS No.: 326827-21-8; 3-Cyclobutyl-1H-pyrazol-5-amine combines cyclobutane's strain energy with pyrazole's hydrogen bonding capacity. ChemShuttle's library of compounds includes such hybrid scaffolds for fragment-based screening. The cyclobutyl group introduces three-dimensionality while the aminopyrazole enables metal-coordination chemistry. Our synthesis employs [2+2] photocycloaddition for cyclobutane formation, followed by regioselective pyrazole cyclization. This compound is particularly useful for metalloenzyme inhibitor development.
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