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3-amino-5-chlorophenol; CAS No.: 883195-40-2;3-amino-5-chlorophenol. PROPERTIES: 3-amino-5-chlorophenol is a chlorinated and aminated phenolic compound with molecular formula C6H6ClNO. It typically exists as a white to off-white crystalline powder with a melting point of approximately 100-105 C. The compound has limited water solubility but dissolves in basic aqueous solutions. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic chlorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from moisture and heat. APPLICATIONS: In pharmaceutical research, this compound serves as a lead structure for developing antimicrobial and anticancer agents. The chloro and amino substitution provides structural diversity that enhances binding to biological targets, while the phenolic hydroxyl group forms hydrogen bonds with catalytic residues (European Journal of Medicinal Chemistry). In materials science, 3-amino-5-chlorophenol contributes to the creation of functional organic materials with tailored electronic properties. Its chlorinated aromatic core and amino group influence the electronic characteristics of derived materials, useful in optoelectronic applications such as organic light-emitting diodes (Journal of Materials Chemistry C). The compound can also form coordination complexes with metal ions, expanding applications in supramolecular chemistry and catalysis (Dalton Transactions).