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3-acetyl-6-chloro-4-phenylquinolin-2(1H)-one; CAS No.: 58375-08-9; ChemShuttle s chloro-phenyl quinolinone serves as a key intermediate for topoisomerase inhibitors. The lactam structure intercalates DNA while the chloro group stabilizes cleavable complexes. The company s custom synthesis services include DNA footprinting studies to validate mechanism of action.