3-(4-(benzyloxy)phenyl)propanoic acid
$150.00
CAS No.: 50463-48-4
Catalog No.: TQP0067
Purity: 95%
MF: C16H16O3
MW: 256.301
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OC1=CC=C(C=C1)CCC(=O)O
Catalog No.: TQP0067
Purity: 95%
MF: C16H16O3
MW: 256.301
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)OC1=CC=C(C=C1)CCC(=O)O
CAS NO.: 50463-48-4;3-(4-(benzyloxy)phenyl)propanoic acid. PROPERTIES: This benzyloxyphenyl propanoic acid presents as a white crystalline solid with a molecular weight of approximately 248.3 g/mol. The 3-(4-(benzyloxy)phenyl)propanoic acid combines a benzyloxyphenyl group with a propanoic acid chain. It exhibits limited aqueous solubility until pH < 4 but dissolves well in DMSO and DMF. Stability characterization reveals vulnerability to acid-catalyzed benzyloxy hydrolysis and base-promoted decarboxylation, necessitating storage at 2-8 degree Celsius in sealed glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause localized edema requiring corticosteroid application. Inhalation may induce respiratory alkalosis; treatment includes humidified oxygen administration. Eye exposure requires chelation inhibitors and ophthalmology evaluation. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The 3-(4-(benzyloxy)phenyl)propanoic acid serves as a key intermediate in the synthesis of various pharmaceuticals. Its benzyloxyphenyl framework provides opportunities for constructing beta-blockers and nonsteroidal anti-inflammatory agents. Research teams utilize this compound as a starting material for creating serotonin receptor modulators and antipsychotic agents. The propanoic acid group undergoes esterification or amide bond formation for further functionalization. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and fluorescent probes for bioimaging applications.
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