The store will not work correctly when cookies are disabled.
We use cookies for optimal website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.
Allow cookies Deny
2-bromo-4-nitrotoluene; CAS No.: 7745-93-9; 2-bromo-4-nitrotoluene. PROPERTIES: 2-bromo-4-nitrotoluene is a crystalline powder with molecular formula C7H6BrNO2. It has a melting point of approximately 40-45 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated, nitro-substituted toluene is used in the development of anticancer prodrugs. The nitro group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 2-bromo-4-nitrotoluene serves as a building block for creating photoaffinity labels. According to biochemical journals, the toluene scaffold provides a fluorescent signal while the bromine and nitro groups enable photoinduced cross-linking with target proteins.