2,4-dibromothiazole-5-carboxylic acid
$200.00
CAS No.: 139669-96-8
Catalog No.: 196056
Purity: 95%
MF: C4HBr2NO2S
MW: 286.932
Storage: 2-8 degree Celsius
SMILES: BrC=1SC(=C(N1)Br)C(=O)O
Catalog No.: 196056
Purity: 95%
MF: C4HBr2NO2S
MW: 286.932
Storage: 2-8 degree Celsius
SMILES: BrC=1SC(=C(N1)Br)C(=O)O
2,4-dibromothiazole-5-carboxylic acid; CAS No.: 139669-96-8; 2,4-dibromothiazole-5-carboxylic acid. PROPERTIES: 2,4-dibromothiazole-5-carboxylic acid is a crystalline solid with molecular formula C4H2Br2NOS, having a molar mass of approximately 285.98 g/mol. It demonstrates low water solubility but good solubility in methylene chloride and dimethylformamide. Melting point determinations typically yield values between 190-194 C. Proper storage requires maintaining in well-sealed containers at temperatures below 20 C, protected from light and moisture. Safety considerations identify it as harmful if swallowed and causing skin irritation. Precautionary measures recommend using explosion-proof ventilation and providing eyewash stations in handling areas. APPLICATIONS: This compound serves as a valuable intermediate in the synthesis of kinase inhibitors, particularly those targeting cancer-related signaling pathways. Its di-brominated thiazole ring enables selective cross-coupling reactions crucial for constructing target molecules. In agrochemical research (non-agricultural context), it contributes to safener compound development through controlled derivatization pathways. Additionally, the compound supports materials science applications in fluorescent probe development for bioimaging, with methodologies published in Journal of Medicinal Chemistry and related pharmaceutical patents, illustrating its significance in oncology and analytical chemistry tools.
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