N-BOC-3-Fluoro-D-phenylalanine(Synonyms: N-BOC-3-Fluoro-D-phenylalanine; N-tert-Butoxycarbonyl-3-fluoro-D-phenylalanine)

Boc-D-Phe(3-F)-OH; (R)-2-(tert-butoxycarbonylamino)-3-(3-fluorophenyl)propanoic acid; CAS No.: 114873-11-9; Boc-D-Phe(3-F)-OH. PROPERTIES: Boc-D-Phe(3-F)-OH is a protected amino acid derivative used in peptide synthesis. This compound has a molecular weight of 312.30 g/mol and appears as a white to slightly yellowish solid. It is sparingly soluble in water but dissolves in organic solvents like DMF and dichloromethane. Boc-D-Phe(3-F)-OH should be stored at room temperature in a dry environment. It is sensitive to moisture and light. Safety precautions include avoiding inhalation and skin contact as it may cause irritation. APPLICATIONS: Boc-D-Phe(3-F)-OH serves as a monomer in the synthesis of peptides containing D-phenylalanine residues with a fluorine substitution at the 3-position. In medicinal chemistry, it facilitates the creation of peptidomimetics with altered electronic properties and binding affinities. In research applications, Boc-D-Phe(3-F)-OH is used to prepare peptides for studying receptor-ligand interactions and enzyme specificity. These applications are referenced in peptide chemistry literature and synthetic organic chemistry publications.