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CAS NO.: 145681-01-2; 1-(tert-butyl) 2-methyl pyrrolidine-1,2-dicarboxylate. PROPERTIES: This protected diamine features a tert-butyl ester and a methyl group on a pyrrolidine ring system, creating a molecule with potential applications in peptide synthesis and organic chemistry. The 1-(tert-butyl) 2-methyl pyrrolidine-1,2-dicarboxylate typically appears as a white to off-white crystalline solid with moderate solubility in common organic solvents. Its molecular structure includes multiple ester groups that can be selectively removed under acidic or basic conditions. For optimal stability and to prevent premature deprotection, this compound should be stored at 2-8 degree Celsius in a tightly sealed container under anhydrous conditions. When handling, appropriate safety measures including nitrile gloves and safety goggles are essential. This compound is sensitive to moisture and may hydrolyze in aqueous environments. In case of accidental spillage, clean the area with a damp cloth and dispose of materials according to local regulations. APPLICATIONS: The 1-(tert-butyl) 2-methyl pyrrolidine-1,2-dicarboxylate serves as a versatile building block in organic synthesis, particularly for creating pyrrolidine-substituted amines. The ester groups provide handles for further functionalization through selective deprotection. In peptide synthesis, this compound functions as a building block for developing peptide mimetics and other bioactive molecules. The methyl substituent contributes to target binding affinity and selectivity. Additionally, the molecule finds utility in materials science as a monomer for creating polymers with specific electronic and optical properties. Researchers utilizing this compound benefit from its functional group versatility, enabling the development of diverse molecular architectures for applications ranging from drug discovery to advanced materials.