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1-(tert-butoxycarbonyl)-4,4-difluoropiperidine-3-carboxylic acid; CAS No.: 1303974-65-3; ChemShuttle's expertise in Small molecules synthesis is showcased through 1-(tert-butoxycarbonyl)-4,4-difluoropiperidine-3-carboxylic acid. This difluorinated piperidine acid acts as a chem block for fluorinated -amino acid synthesis. The gem-difluoro substitution creates a rigidified chair conformation that mimics proline's structural effects in peptides. Applications include fluorinated collagen mimics and protease-resistant peptide therapeutics. The company offers enantiomeric separation services with chiral SFC, providing both (R) and (S) configurations for structure-activity studies. Technical data includes circular dichroism spectra demonstrating helical induction in model peptides.