benzyl trans-3-hydroxycyclobutanecarboxylate
$350.00
CAS No.: 128041-58-7
Catalog No.: 195567
Purity: 95%
MF: C12H14O3
MW: 206.241
Storage: 2-8 degree Celsius
SMILES: O[C@@H]1C[C@H](C1)C(=O)OCC1=CC=CC=C1
Catalog No.: 195567
Purity: 95%
MF: C12H14O3
MW: 206.241
Storage: 2-8 degree Celsius
SMILES: O[C@@H]1C[C@H](C1)C(=O)OCC1=CC=CC=C1
benzyl trans-3-hydroxycyclobutanecarboxylate; CAS No.: 128041-58-7; benzyl trans-3-hydroxycyclobutanecarboxylate. PROPERTIES: Benzyl trans-3-hydroxycyclobutanecarboxylate is a colorless oil with molecular formula C12H14O3. It demonstrates a boiling point around 140-145 C at 10 mmHg and moderate thermal stability. The compound exhibits good solubility in ethyl acetate and moderate solubility in methylene chloride. Recommended storage requires keeping it in tightly sealed containers at 2-8 C under nitrogen atmosphere to prevent oxidation. Safety precautions involve using appropriate eye protection to avoid injury from splashing liquids and avoiding prolonged inhalation of vapors. APPLICATIONS: This benzyl-protected hydroxy ester serves as a key intermediate in the synthesis of beta-adrenergic receptor antagonists, where the benzyl trans-3-hydroxycyclobutanecarboxylate group provides steric and electronic features conducive to receptor binding (Journal of Medicinal Chemistry). In organic synthesis, the compound is used as a building block for constructing medium-sized carbocycles through ring-opening reactions (Synthesis). Furthermore, its ester functionality enables hydrolysis reactions for the preparation of corresponding carboxylic acids used in bioactive molecule development (Bioorganic & Medicinal Chemistry Letters).
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