benzyl 4-chloro-3-oxobutanoate
$300.00
CAS No.: 32807-27-5
Catalog No.: 193807
Purity: 95%
MF: C11H11ClO3
MW: 226.659
Storage: 2-8 degree Celsius
SMILES: ClCC(CC(=O)OCC1=CC=CC=C1)=O
Catalog No.: 193807
Purity: 95%
MF: C11H11ClO3
MW: 226.659
Storage: 2-8 degree Celsius
SMILES: ClCC(CC(=O)OCC1=CC=CC=C1)=O
benzyl 4-chloro-3-oxobutanoate; CAS No.: 32807-27-5;benzyl 4-chloro-3-oxobutanoate. PROPERTIES: Benzyl 4-chloro-3-oxobutanoate is a chlorinated keto ester with molecular formula C12H11ClO3. It typically exists as a colorless liquid with a mild ester-like odor, having a boiling point around 220-225 C. The compound has limited water solubility but dissolves well in organic solvents like ether or chloroform. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong bases, releasing chlorinated byproducts. Storage should be in amber glass bottles at temperatures below 25 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a building block for constructing complex molecules through its reactive keto and ester groups. The chloro substituent provides a site for nucleophilic substitution reactions, enabling diversification of the molecular framework (Synlett). In pharmaceutical development, benzyl 4-chloro-3-oxobutanoate contributes to the synthesis of -lactam antibiotics and other heterocyclic compounds where the ϫ-keto ester motif is essential for biological activity (Journal of Antibiotics). Its benzyl protecting group allows for temporary protection of the ester functionality, which can be removed under mild conditions to introduce additional functionality in later synthetic steps (Tetrahedron).
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