benzyl 3,3-difluoropyrrolidine-1-carboxylate
$200.00
CAS No.: 163457-22-5
Catalog No.: 192999
Purity: 95%
MF: C12H13F2NO2
MW: 241.237
Storage: 2-8 degree Celsius
SMILES: FC1(CN(CC1)C(=O)OCC1=CC=CC=C1)F
Catalog No.: 192999
Purity: 95%
MF: C12H13F2NO2
MW: 241.237
Storage: 2-8 degree Celsius
SMILES: FC1(CN(CC1)C(=O)OCC1=CC=CC=C1)F
benzyl 3,3-difluoropyrrolidine-1-carboxylate; CAS No.: 163457-22-5; benzyl 3,3-difluoropyrrolidine-1-carboxylate. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C11H13F2N2O2 and a molecular weight of 237.23 g/mol. It exhibits a melting point in the range of 108-112 C and demonstrates moderate solubility in common organic solvents like dichloromethane and acetone. The substance is sensitive to photodegradation and should be stored in amber containers. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from light and moisture. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as benzyl 3,3-difluoropyrrolidine-1-carboxylate may release toxic fumes upon heating. The difluoro substituents require careful handling in strongly basic environments. APPLICATIONS: In medicinal chemistry, benzyl 3,3-difluoropyrrolidine-1-carboxylate serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its difluoro substituents enable improved metabolic stability in biological systems. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through nucleophilic aromatic substitution reactions. Academic studies have explored its potential in the development of fluorescent probes for bioimaging applications, as reported in biochemical journals. The pyrrolidine ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.
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