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8-(methylsulfonyl)quinoline-3-carboxylic acid; CAS No.: 1956331-41-1; 8-(methylsulfonyl)quinoline-3-carboxylic acid. PROPERTIES: 8-(methylsulfonyl)quinoline-3-carboxylic acid is a solid compound with a molecular weight of 263.3 g/mol. It has a melting point ranging from 215 to 218 C (decomposition) and is moderately soluble in polar organic solvents such as dimethylformamide and dimethyl sulfoxide. The compound is sensitive to light and should be stored in amber glass containers. It is stable under normal laboratory conditions but may decompose upon exposure to strong oxidizing agents. When handling, care should be taken to avoid skin contact and inhalation of vapors. APPLICATIONS: 8-(methylsulfonyl)quinoline-3-carboxylic acid functions as a versatile intermediate in the synthesis of pharmaceuticals, particularly in the development of anticancer and antiviral agents. The carboxylic acid group provides a site for further modification, such as esterification or amide formation. In medicinal chemistry, 8-(methylsulfonyl)quinoline-3-carboxylic acid is used to create compounds with improved pharmacokinetic profiles. It also serves as a building block in the synthesis of fluorescent dyes, where its quinoline core contributes to emission characteristics. Additionally, the compound is employed in the preparation of coordination compounds with metal ions for catalytic applications in organic synthesis. These uses are typically encountered in pharmaceutical R&D departments and specialized chemical synthesis laboratories.