7-(trifluoromethyl)isoquinolin-4-ol
$300.00
CAS No.: 2566172-43-6
Catalog No.: 192242
Purity: 95%
MF: C10H6F3NO
MW: 213.158
Storage: 2-8 degree Celsius
SMILES: FC(C1=CC=C2C(=CN=CC2=C1)O)(F)F
Catalog No.: 192242
Purity: 95%
MF: C10H6F3NO
MW: 213.158
Storage: 2-8 degree Celsius
SMILES: FC(C1=CC=C2C(=CN=CC2=C1)O)(F)F
7-(trifluoromethyl)isoquinolin-4-ol; CAS No.: 2566172-43-6; 7-(trifluoromethyl)isoquinolin-4-ol. PROPERTIES: 7-(trifluoromethyl)isoquinolin-4-ol is a white to off-white crystalline powder with molecular weight 223.15 g/mol. It has a melting point between 210-215 C and shows limited aqueous solubility but good solubility in DMSO. Proper storage requires a tightly sealed container at room temperature away from acidic vapors. Safety precautions include wearing protective gloves and eye protection as this compound may cause skin and eye irritation. APPLICATIONS: This trifluoromethyl-substituted isoquinoline alcohol is employed in the development of antimicrobial agents. The hydroxyl group at position 4 allows for glycosylation, creating fluoroquinolone antibiotics with enhanced antibacterial spectra as reported in pharmaceutical chemistry journals. In bioanalytical applications, 7-(trifluoromethyl)isoquinolin-4-ol serves as a fluorescent probe for detecting specific metal ions. According to analytical chemistry research, the isoquinoline scaffold's fluorescence is quenched upon metal coordination, enabling sensitive detection methods with limits approaching nanomolar concentrations.
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