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7-chloroisoquinolin-1(2H)-one; CAS No.: 24188-74-7; ChemShuttle provides key intermediates like this chloroisoquinolinone for PARP inhibitor synthesis. The 7-chloro substituent and lactam structure mimic nicotinamide pharmacophores. Our Friedl?nder annulation achieves regioselective quinoline formation. The product enables development of olaparib analogs with enhanced DNA repair inhibition for BRCA-mutant cancer treatment.