7-amino-4-(trifluoromethyl)quinolin-2(1H)-one
$350.00
CAS No.: 58721-76-9
Catalog No.: 192343
Purity: 95%
MF: C10H7F3N2O
MW: 228.173
Storage: 2-8 degree Celsius
SMILES: NC1=CC=C2C(=CC(NC2=C1)=O)C(F)(F)F
Catalog No.: 192343
Purity: 95%
MF: C10H7F3N2O
MW: 228.173
Storage: 2-8 degree Celsius
SMILES: NC1=CC=C2C(=CC(NC2=C1)=O)C(F)(F)F
7-amino-4-(trifluoromethyl)quinolin-2(1H)-one; CAS No.: 58721-76-9; 7-amino-4-(trifluoromethyl)quinolin-2(1H)-one. PROPERTIES: 7-amino-4-(trifluoromethyl)quinolin-2(1H)-one is a crystalline compound with molecular formula C10H7F3N2O. It has a melting point between 200-205 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This amino, trifluoromethyl-substituted quinone is used in the development of anticancer prodrugs. The amino group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 7-amino-4-(trifluoromethyl)quinolin-2(1H)-one serves as a building block for creating photoaffinity labels. According to biochemical journals, the quinone scaffold provides a fluorescent signal while the trifluoromethyl group enables photoinduced cross-linking with target proteins.
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