5-methyl-1H-indazol-4-ol
$300.00
CAS No.: 1360968-74-6
Catalog No.: 195540
Purity: 95%
MF: C8H8N2O
MW: 148.165
Storage: 2-8 degree Celsius
SMILES: CC1=C(C=2C=NNC2C=C1)O
Catalog No.: 195540
Purity: 95%
MF: C8H8N2O
MW: 148.165
Storage: 2-8 degree Celsius
SMILES: CC1=C(C=2C=NNC2C=C1)O
5-methyl-1H-indazol-4-ol; CAS No.: 1360968-74-6; 5-methyl-1H-indazol-4-ol. PROPERTIES: 5-methyl-1H-indazol-4-ol is a crystalline solid with molecular formula C9H8N2O. It exhibits a melting point range of 135-138 C and moderate thermal stability. The compound shows good solubility in methanol and moderate solubility in water. Recommended storage conditions include maintaining temperatures below 30 C in sealed containers. Safety precautions involve using eye/face protection with side shields to prevent injury from splashing liquids and avoiding release into the environment to prevent ecological harm. APPLICATIONS: This methylated indazole derivative serves as a key intermediate in the synthesis of sphingosine-1-phosphate receptor modulators used in multiple sclerosis treatment, where the 5-methyl-1H-indazol-4-ol group facilitates receptor binding (Nature Reviews Drug Discovery). In materials science, the compound is incorporated into molecularly imprinted polymers for selective recognition of target analytes in complex mixtures (Journal of Chromatography A). Additionally, its hydroxyl group enables phosphorylation reactions for the development of kinase inhibitors with improved selectivity profiles (Bioorganic & Medicinal Chemistry Letters).
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