5-fluoropicolinohydrazide
$200.00
CAS No.: 1254073-41-0
Catalog No.: 193123
Purity: 95%
MF: C6H6FN3O
MW: 155.132
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC(=NC1)C(=O)NN
Catalog No.: 193123
Purity: 95%
MF: C6H6FN3O
MW: 155.132
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC(=NC1)C(=O)NN
5-fluoropicolinohydrazide; CAS No.: 1254073-41-0 5-fluoropicolinohydrazide. PROPERTIES: 5-fluoropicolinohydrazide is a crystalline solid with a molecular weight of 152.1 g/mol. Its melting point typically ranges between 165-170 C. This compound exhibits moderate solubility in water and is more soluble in organic solvents like DMSO and DMF. When handling 5-fluoropicolinohydrazide, protective equipment including gloves, eye protection, and a lab coat should be worn to prevent skin and inhalation exposure. The compound should be stored in a tightly sealed container at temperatures below 20 C, preferably in a desiccator to protect against moisture. It is advisable to avoid exposure to strong oxidizing agents and acidic conditions. APPLICATIONS: 5-fluoropicolinohydrazide serves as a valuable intermediate in the synthesis of pharmaceuticals, particularly in the development of antimicrobial and antiviral agents. Its hydrazide functionality allows for further chemical modification, making it a flexible building block in medicinal chemistry. In recent research, derivatives of this compound have shown promise in inhibiting specific bacterial enzymes, which is detailed in the Journal of Medicinal Chemistry. Additionally, 5-fluoropicolinohydrazide can be utilized in the preparation of heterocyclic compounds through condensation reactions, as reported in Organic Syntheses. The compound's fluorinated structure also makes it suitable for studying enzyme-substrate interactions in biochemical assays, as demonstrated in Bioorganic & Medicinal Chemistry Letters.
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