(5-bromo-2-chlorophenyl)methanamine
$300.00
CAS No.: 1096296-85-3
Catalog No.: 196505
Purity: 95%
MF: C7H7BrClN
MW: 220.497
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC(=C(C1)CN)Cl
Catalog No.: 196505
Purity: 95%
MF: C7H7BrClN
MW: 220.497
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC(=C(C1)CN)Cl
(5-bromo-2-chlorophenyl)methanamine; CAS No.: 1096296-85-3; (5-bromo-2-chlorophenyl)methanamine. PROPERTIES: (5-bromo-2-chlorophenyl)methanamine appears as a colorless to pale yellow liquid. Its molecular formula is C7H7BrClN, corresponding to a molecular weight of 231.5 g/mol. The compound exhibits moderate solubility in common organic solvents such as dichloromethane, ethyl acetate, and tetrahydrofuran, but limited water solubility. It has a boiling point ranging from 150-155 C at 760 mmHg and a density of approximately 1.5 g/cm?. The material is stable under normal laboratory conditions when stored properly. Recommended storage involves keeping the compound in a tightly sealed container at room temperature (15-25 C), preferably in a cool, dry, and well-ventilated area away from heat sources and direct sunlight. The compound is moderately flammable and should be stored away from ignition sources. Safety precautions include wearing appropriate personal protective equipment such as chemical-resistant gloves and eye protection when handling the material. In case of skin contact, washing with soap and water is advised, and eye contact requires thorough rinsing with water for at least 15 minutes. The compound should be handled in well-ventilated areas to minimize vapor inhalation risks. APPLICATIONS: (5-bromo-2-chlorophenyl)methanamine serves as a valuable building block in pharmaceutical chemistry, particularly in the development of targeted kinase inhibitors and receptor modulators. The presence of both bromo and chloro substituents provides versatile sites for cross-coupling reactions and bioisosteric replacements. In medicinal chemistry research, the compound has been utilized as a core structure in the synthesis of novel anticancer agents targeting specific oncogenic pathways, as documented in various pharmaceutical research publications. The methanamine functionality offers a suitable platform for the design of bioactive molecules with improved binding affinity and selectivity. Additionally, (5-bromo-2-chlorophenyl)methanamine finds application in materials science as a building block for organic light-emitting diodes and in the development of fluorescent probes for bioimaging applications. Its utility extends to analytical chemistry, where it serves as a reference standard for chromatographic analyses and as a starting material for custom syntheses in specialized laboratories focusing on heterocyclic chemistry and medicinal applications. The compound's electronic properties make it suitable for incorporation into molecular sensors and as a component in luminescent materials for optical devices.
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