5-amino-1-phenyl-1H-pyrazole-4-carboxamide
$200.00
CAS No.: 50427-77-5
Catalog No.: 192879
Purity: 95%
MF: C10H10N4O
MW: 202.217
Storage: 2-8 degree Celsius
SMILES: NC1=C(C=NN1C1=CC=CC=C1)C(=O)N
Catalog No.: 192879
Purity: 95%
MF: C10H10N4O
MW: 202.217
Storage: 2-8 degree Celsius
SMILES: NC1=C(C=NN1C1=CC=CC=C1)C(=O)N
5-amino-1-phenyl-1H-pyrazole-4-carboxamide; CAS No.: 50427-77-5; 5-amino-1-phenyl-1H-pyrazole-4-carboxamide. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C10H9N4O and a molecular weight of 203.20 g/mol. It demonstrates a melting point in the range of 202-206 C and shows moderate solubility in polar solvents such as water and methanol. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 5-amino-1-phenyl-1H-pyrazole-4-carboxamide may cause skin and eye irritation. The amine group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, 5-amino-1-phenyl-1H-pyrazole-4-carboxamide serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on pyrazole derivatives. Its amino substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through coupling reactions. Academic research has explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The pyrazole ring system also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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