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4-nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate; CAS No.: 491878-06-9; ChemShuttle s building blocks for drug discovery include this sulfamoyl-pyrrolidine for protease inhibitor development. The Boc-protected sulfamoyl group enables controlled deprotection during synthesis. Our Mitsunobu reaction achieves complete inversion at the 4-position. The product serves as a key intermediate for HCV NS3/4A protease inhibitors, supporting antiviral drug development.