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4-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride; CAS No.: 41566-80-7; 4-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride. PROPERTIES: This compound is a 4-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride appearing as white hygroscopic powder. Its molecular weight is approximately 211.26 g/mol (free base). It has sharp melting point around 185-190 C (with decomposition). The compound is highly soluble in water and polar organic solvents. It's moisture sensitive and may absorb atmospheric moisture readily. Store in tightly sealed containers under dry conditions. Keep below 25 C and protect from humidity. Handle with care using appropriate engineering controls to prevent dust inhalation. APPLICATIONS: 4-methoxy-2,3-dihydro-1H-inden-1-amine hydrochloride is utilized in pharmaceutical research as intermediate for serotonin-norepinephrine reuptake inhibitors as detailed in Journal of Medicinal Chemistry. It's employed in synthesis of certain anxiolytic compounds mentioned in European Journal of Medicinal Chemistry. Additionally, this compound serves as starting material for preparing indane-based muscarinic receptor modulators reported in Journal of Organic Chemistry. The methoxy group provides electron-donating effect beneficial in receptor binding studies.