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(4-fluorobenzyl)hydrazine hydrochloride; CAS No.: 1059626-05-9; (4-fluorobenzyl)hydrazine hydrochloride. PROPERTIES: This fluoro-substituted benzylhydrazine salt features molecular formula C?H?FNN?O? with molecular weight 197.65 g/mol. It generally appears as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 150-155 C (decomposition). Exhibits IR absorption for hydrazine N-H groups (~3300-3000 cm??) and C-F groups (~1300-1100 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause severe skin burns and eye damage; therefore, rigorous containment and personal protection measures are essential during manipulation. APPLICATIONS: As a fluoro-substituted benzylhydrazine, (4-fluorobenzyl)hydrazine hydrochloride is predominantly utilized in the synthesis of antiviral agents. It serves as a key intermediate in constructing nucleoside analogs, where the hydrazine group undergoes selective glycosylation reactions to form bioactive derivatives as demonstrated in medicinal chemistry research (Antiviral Research). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its hydrazine functionality enables conjugation to biomolecules via reductive amination (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing hydrazine-based crosslinking agents for protein immobilization, where the hydrazine group forms covalent bonds with aldehyde-containing surfaces (ACS Applied Materials & Interfaces).