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4-fluoro-1H-pyrazole-3-carboxylic acid; CAS No.: 881668-91-3; 4-fluoro-1H-pyrazole-3-carboxylic acid. PROPERTIES: This compound is a 4-fluoro-1H-pyrazole-3-carboxylic acid appearing as white crystalline powder. Its molecular weight is approximately 139.07 g/mol. It has melting point around 160-165 C. The compound is moderately soluble in polar organic solvents like dimethylformamide. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 25 C and protect from moisture. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: 4-fluoro-1H-pyrazole-3-carboxylic acid is utilized in organic synthesis as pyrazole building block containing fluorine substituent as detailed in Synthetic Communications. It's employed in preparation of certain herbicides mentioned in Pest Management Science. Additionally, this compound serves as intermediate for synthesizing pyrazole-containing pharmaceuticals reported in Journal of Medicinal Chemistry. The fluorine atom provides valuable electron-withdrawing effect beneficial in agrochemical applications.