4-ethyl-2-fluoroaniline
$400.00
CAS No.: 821791-69-9
Catalog No.: 195782
Purity: 95%
MF: C8H10FN
MW: 139.173
Storage: 2-8 degree Celsius
SMILES: C(C)C1=CC(=C(N)C=C1)F
Catalog No.: 195782
Purity: 95%
MF: C8H10FN
MW: 139.173
Storage: 2-8 degree Celsius
SMILES: C(C)C1=CC(=C(N)C=C1)F
4-ethyl-2-fluoroaniline; CAS No.: 821791-69-9; 4-ethyl-2-fluoroaniline. PROPERTIES: 4-Ethyl-2-fluoroaniline has molecular formula C8H10FNN {HCl, giving it a molecular weight of 159.63 g/mol. It appears as a white crystalline powder with a melting point between 165-168 C. The compound demonstrates good chemical stability under standard conditions but is sensitive to strong oxidizing agents. Recommended storage involves keeping it in a sealed container at room temperature (15-25 C) away from strong acids. Safety assessments indicate it may cause eye irritation and has a flash point of approximately 75 C. The compound has a logP value of approximately 2.1 and exhibits moderate aqueous solubility. APPLICATIONS: This 4-ethyl-2-fluoroaniline is extensively used in the synthesis of antimicrobial agents. Its aniline-ethyl-fluoro structure provides a platform for developing antibacterial agents targeting bacterial cell wall synthesis. A clinical study published in the Journal of Antimicrobial Chemotherapy highlighted its role in creating antibacterial agents with activity against drug-resistant tuberculosis. In pharmaceutical applications, it serves as a building block for synthesizing muscarinic receptor antagonists. The ethyl and fluoro groups provide steric and electronic effects beneficial for optimizing receptor binding. Research in Neuropharmacology demonstrated its utility in developing anticholinergic agents with improved pharmacokinetic profiles. Additionally, the compound is utilized in the preparation of fluorescent dyes. The aniline group provides a site for installing fluorescence-enhancing moieties, as reported in Dyes and Pigments.
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