4-chloro-7-methyl-1H-indazole
$200.00
CAS No.: 1427430-82-7
Catalog No.: 192656
Purity: 95%
MF: C8H7ClN2
MW: 166.611
Storage: 2-8 degree Celsius
SMILES: ClC1=C2C=NNC2=C(C=C1)C
Catalog No.: 192656
Purity: 95%
MF: C8H7ClN2
MW: 166.611
Storage: 2-8 degree Celsius
SMILES: ClC1=C2C=NNC2=C(C=C1)C
4-chloro-7-methyl-1H-indazole; CAS No.: 1427430-82-7; 4-chloro-7-methyl-1H-indazole. PROPERTIES: This chlorinated, methyl-substituted indazole has molecular formula C8H7ClN3. It typically appears as a pale yellow crystalline powder. The 4-chloro-7-methyl-1H-indazole demonstrates limited water solubility but good solubility in common organic solvents like methanol and ethyl acetate. Its melting point ranges between 110-113 C, and it has a molecular weight of approximately 170.61 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong bases and may decompose upon exposure to high temperatures above 150 C. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The 4-chloro-7-methyl-1H-indazole functions as a valuable intermediate in the synthesis of adenosine receptor antagonists for cardiovascular indications where the chloro and methyl groups provide essential binding interactions with receptor subtypes (as reported in medicinal chemistry literature). The methyl group enhances metabolic stability by preventing oxidative degradation. Additionally, the compound serves as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The chloro atom can be further functionalized through nucleophilic substitution reactions to produce various derivatives for chemical research applications.
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